diff --git a/meta-python/recipes-devtools/python/python3-m2crypto/avoid-host-contamination.patch b/meta-python/recipes-devtools/python/python3-m2crypto/avoid-host-contamination.patch
new file mode 100644
index 000000000..9d9b8449b
--- /dev/null
+++ b/meta-python/recipes-devtools/python/python3-m2crypto/avoid-host-contamination.patch
@@ -0,0 +1,23 @@
+Filter out '/usr/include' for swig to avoid host contamination issue.
+
+Upstream-Status: Upstream-Status: Inappropriate [cross compile specific]
+
+Signed-off-by: Kai Kang <kai.kang@windriver.com>
+---
+ setup.py | 3 ++-
+ 1 file changed, 2 insertions(+), 1 deletion(-)
+
+diff --git a/setup.py b/setup.py
+index 5a12981..389d49f 100644
+--- a/setup.py
++++ b/setup.py
+@@ -153,7 +153,8 @@ class _M2CryptoBuildExt(build_ext.build_ext):
+             self.swig_opts.append('-py3')
+ 
+         # swig seems to need the default header file directories
+-        self.swig_opts.extend(['-I%s' % i for i in _get_additional_includes()])
++        self.swig_opts.extend(['-I%s' % i for i in _get_additional_includes()
++                                            if i != '/usr/include'])
+ 
+         log.debug('self.include_dirs = %s', self.include_dirs)
+         log.debug('self.library_dirs = %s', self.library_dirs)
diff --git a/meta-python/recipes-devtools/python/python3-m2crypto_0.37.1.bb b/meta-python/recipes-devtools/python/python3-m2crypto_0.37.1.bb
index 2284a43a3..b3da87fb7 100644
--- a/meta-python/recipes-devtools/python/python3-m2crypto_0.37.1.bb
+++ b/meta-python/recipes-devtools/python/python3-m2crypto_0.37.1.bb
@@ -10,6 +10,7 @@ SRC_URI += "file://0001-setup.py-link-in-sysroot-not-in-host-directories.patch \
             file://cross-compile-platform.patch \
             file://0001-Allow-verify_cb_-to-be-called-with-ok-True.patch \
             file://0001-Use-of-RSA_SSLV23_PADDING-has-been-deprecated.patch \
+            file://avoid-host-contamination.patch \
            "
 SRC_URI[sha256sum] = "e4e42f068b78ccbf113e5d0a72ae5f480f6c3ace4940b91e4fff5598cfff6fb3"
 
@@ -42,4 +43,6 @@ SWIG_FEATURES_append_mipsarch = " -D_MIPS_SZPTR=${SITEINFO_BITS}"
 SWIG_FEATURES_append_powerpc64le = " -D__powerpc64__"
 export SWIG_FEATURES
 
+export STAGING_DIR
+
 BBCLASSEXTEND = "native"